The University of Osaka (UOsaka) traces its origins to Tekijuku, a private “place of learning” founded by OGATA Koan in 1838. A scholar of Western medicine, OGATA established a private school and clinic in Kawara-machi, Osaka, where students studied Western medicine and medical practice.
Seven years later, Tekijuku was relocated to Kasho-machi, now 3 Kitahama, Chuo-ku, Osaka, where much of the original school building still remains. Tekijuku subsequently became an important center for vaccination research and cholera treatment. In 1846, OGATA established Jotokan, which became the first smallpox vaccination institution officially recognized by the Edo government in 1858.